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Companion Animals

The health and well-being of companion animals, such as dogs and cats, are a growing area of interest. Microbiome research is transforming how we understand animal health, revealing connections between microbial communities and conditions like allergies, gastrointestinal issues, infections, and even behavior. At Cmbio, we offer a comprehensive suite of multi-omics services designed to unlock the full potential of microbiome research in companion animal care.

Our Expertise in Companion Animal Research

We provide tailored microbiome profiling and analysis services to help companion animal companies and researchers explore the bacterial communities in various body sites, such as the gut, skin, or oral cavity. These insights can guide the development of more effective diagnostics, treatments, and nutrition products that improve animal health.
 

Microbiome Sequencing, Profiling, and Analysis

Using long-read 16S sequencing or shotgun metagenomics, we accurately and sensitively provide taxonomic and functional compositions, enabling further analysis to reveal links between the microbiome and companion animal health.

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De Novo Long-Read Metagenomics

We specialize in de novo long-read metagenomics, a powerful approach for generating high-quality reference databases where existing ones are limited, such as for many animal-associated microbiomes. Long-read sequencing enables us to assemble complete genomes, providing deeper insights into microbial communities and their functional potential.

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Probiotic and Therapeutic Development

By combining metagenomics with clonal-level profiling and strain tracking, we help identify beneficial microbial strains for the development of probiotics and therapeutics. Our microbial isolate sequencing further supports precise strain identification for targeted interventions.

 

 

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Health and Disease Biomarker Discovery

With our multi-omics approach, including metagenomics, metatranscriptomics, and metabolomics, we help identify biomarkers linked to conditions such as gastrointestinal issues, allergies, and infections. These biomarkers can support the development of diagnostic tests or personalized therapies to improve veterinary care.

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Diet and Nutrition Optimization

Understanding how diet influences the microbiome is critical for developing optimized pet foods. By leveraging targeted metabolomics panels, such as the short-chain fatty acid panel and amino acid and TCA panel, we assess how dietary interventions impact metabolic pathways and gut health. These insights help companies formulate products that promote a balanced, healthy microbiome for companion animals.

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Gut-Brian Axis Research

For companies exploring the connection between the gut microbiome and behavioral health in companion animals, our targeted metabolomics panels focus on key metabolites, such as SCFAs and tryptophan metabolites, which are involved in the gut-brain axis. Furthermore, using shotgun metabolomics, we provide functional profiling of Gut-Brain functional modules.

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