Infectious Diseases and Antimicrobial Resistance

The rise of antimicrobial resistance (AMR) and the spread of infectious diseases are critical global health challenges. Understanding the microbiome’s role in these issues can provide new avenues for diagnostics, treatments, and prevention strategies. At Cmbio, we offer advanced microbiome research tools to explore the complex microbial interactions in infectious diseases and identify resistance mechanisms, helping to develop better-targeted interventions and therapies.

 

AMR Profiling from Shotgun Data

Our shotgun metagenomics services provide comprehensive profiling of antimicrobial resistance genes within microbial communities. This allows for the identification of resistant strains and the assessment of the overall AMR landscape, which is critical for understanding resistance patterns and guiding treatment decisions.

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Microbial Strain Characterization

We offer strain-level characterization by using long-read sequencing to analyze bacterial isolates in order to retrieve reference-grade, closed genomes and identify resistant genes and virulence factors.

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Metabolomics

Our metabolomics services, with a focus on bile acids, provide insights into the metabolic activity of microbial communities in infectious diseases. Bile acids play a significant role in microbial-host interactions during infection.

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Virulence and Pathogen Profiling

We provide bioinformatic tools to profile microbial virulence factors and pathogenicity in metagenomic samples. By analyzing these elements, we help researchers understand how certain strains cause disease and contribute to the spread of infections.

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Efficient and Cost-Effective Pathogen Detection Using LR 16S

 Our long-read 16S sequencing pipeline offers rapid and affordable analysis of metagenomic samples. The taxonomic resolution is high compared to traditional short-read amplicon methods and is suitable for pathogen detection, providing microbial identification that is both time-efficient and cost-effective. This service is ideal for tracking pathogens in a wide range of samples.

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