Metabolomics

Metabolomics—the large-scale study of small molecules known as metabolites—provides a real-time snapshot of metabolic processes in biological systems. It’s essential for microbiome research, illuminating how microbial communities function and interact with the human host to promote health or cause disease.

Supporting Pharma, Biotech, Clinical & Academic Science

Supporting pharma, biotech, clinical & academic science, our state-of-the-art metabolomics services empower investigators to realize their research objectives through robust LC-MS/MS workflows and advanced data analysis. Our multi-omics scientists deliver rigorous technical depth with high-resolution mass spectrometry based assays—making Cmbio a leading partner for metabolomics research using a diverse range of biological samples.

1. Proven Scientific Expertise

Targeted and untargeted LC-MS/MS metabolomics backed by 15+ years of development and peer-reviewed scientific leadership.

2. Full Transparency in Every Project

Complete access to raw data, metadata, QC and methods, ensuring full traceability and regulatory-ready outputs.

3. A Science-Driven Partnership

Work directly with multi-omics experts for deeper interpretation, robust study design and freedom from restrictive software workflows.

The Challenge in Modern Metabolomics

Metabolomics projects carry significant scientific and operational risk. Data quality can vary by provider and is affected by sample types, quantification methods, and the coverage of different metabolites. Limited transparency—especially in negative ion modes or negative mode analyses—makes it difficult for researchers to validate findings, analyze metabolic pathways, and ensure reproducible detection of small molecules, lipids, and fatty acids critical for health studies, diabetes research, and biomarker discovery.

Adding to this, metabolomics requires deep expertise in LC-MS/MS, complex workflows and multi-omics integration. Without expert interpretation, studies can lose biological relevance, overlook key metabolites or generate outputs that are difficult to defend in regulatory or scientific review.

Each metabolomics study features full methodological documentation, including internal standards, raw files, QC summaries, and retention time mapping for complete traceability.

Our expert scientists collaborate with researchers in method selection, metabolite identification, and biological contextualization to deliver actionable, publication-ready insights.

Customizable panels address diverse sample types—plasma, serum, cells, tissues—with tailored quantification strategies for various metabolic pathways.

1. Full Transparency

Raw data, metadata and QC included, regulatory-ready, no black boxes.

2. Expert Interpretation

Direct access to our scientists for clear, publication-ready insights.

3. GxP-Strengthened Workflows

Processes aligned with pharma and clinical research standards.

4. Fast Turnaround

Flexible timelines, from 2 weeks, depending on your study needs.

5. Pharma-Grade Reporting

High-quality, structured reports with full traceability and QC summaries.

6. Multi-Omics Integration

Combine metabolomics with metagenomics, proteomics or genomics for deeper biological context.

Know More About Our Metabolomics Capabilities

Metabolomics, the large-scale study of small molecules known as metabolites, provides a real-time snapshot of metabolic processes in biological systems. It’s essential for microbiome research, illuminating how microbial communities function and interact with the human host to promote health or cause disease.

At Cmbio, our dedicated metabolomics team offers a comprehensive range of services to meet your needs, accommodating both novices and experienced researchers. Collaborate directly with our specialized scientists for guidance on analytical chemistry, method selection, technical analysis details, and advanced data processing and interpretation.

Tailored to your specific requirements, our metabolomics platforms offer both untargeted and targeted metabolomics analyses.

Untargeted Metabolomics Panels

Untargeted metabolomics provides global detection of broad compound classes produced by the host and the microbiome that play crucial roles in microbial metabolism and host-microbe interactions. While the specific composition may vary depending on the sample type and experimental conditions, here are some of the relevant compound classes commonly detected.

Microbial metabolites refer to the small molecules produced by microorganisms and have various roles and significance. They provide a detailed snapshot of the metabolic status of microbial communities and offer insights into the biochemical pathways and processes of the microorganisms to enable an understanding of how microbes interact with their environment, utilize resources, respond to external stimuli and potential implications for driving health and disease.

Our untargeted methods include analysis of common microbial metabolites such as TMAO, bile acids, tryptophan, tryptophan-derived metabolites, acylcarnitines, amino acids, citric acid cycle compounds, phosphatidylcholine and carnitine

Targeted Metabolomics Panels

To complement our untargeted analyses, we offer specialized targeted metabolomics panels that focus on specific groups of metabolites relevant to your research. These panels provide precise quantification of compounds within key metabolic pathways, enabling deeper insights into biological functions and disease mechanisms.

Short-Chain Fatty Acid Panel

Quantifies essential fatty acids like acetate, butyrate, and propionate, crucial for gut health and metabolic regulation.

Acetic acid aka acetate (HMDB0000042)
Butanoic acid aka butyrate (HMDB0000039)
Heptanoic acid (HMDB0000666)
Hexanoic acid aka caproic acid (HMDB0000535)
Pentanoic acid aka valerate, valeric acid (HMDB0000892)
2-methylpropanoic acid aka isobutyrate, isobutyric acid (HMDB0001873)
3-Methylbutanoic acid aka isovalerate, isovaleric acid (HMDB0000718)
Formic acid aka formate (HMDB0000142)
Propanoic acid aka propionate (HMDB0000237)
4-Methylpentanoic acid aka isocaproic acid (HMDB0000689)
2-Methylbutyric acid (HMDB0033742) [NEW]
2-Methyl pentanoic acid aka 2-Methylvaleric acid (HMDB0031580) [NEW]
3-Methyl pentanoic acid aka 3-Methylvaleric acid (HMDB0033774) [NEW]

Customised Metabolomics Solutions

At Cmbio, we understand that every research question is unique. That’s why we offer fully customised metabolomics solutions to support your specific study design, from early-stage concept to advanced data interpretation.

Whether you're exploring microbial-host interaction studies, investigating disease mechanisms, or seeking precision in microbiome metabolite analysis, our LC-MS/MS metabolomics platforms provide flexible, high-resolution metabolic profiling across diverse sample types.

You’ll work closely with our expert team for tailored method development, selection of the most relevant metabolite panels, and in-depth metabolomics data interpretation. We also offer research metabolomics consulting to help refine your hypotheses, optimise your experimental workflow, and generate robust, publication-ready results.

Metabolomics powered by Multi-Omics

Beyond metabolomics, our scientists can guide you in integrating additional omics layers to strengthen biological interpretation and unlock deeper, more actionable insights.

Talk With Our Experts

Metabolomics Services Tailored to Your Research Needs